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PHILADELPHIA, PENNSYLVANIA - Millions of asbestos fibers have been found throughout the Philadelphia school district, according to a joint investigation by The Inquirer and Daily News. The investigation sought to uncover dangerous substances in Philadelphia schools, including asbestos, lead, and mold. Teachers from 11 schools collected samples, which were then analyzed by the International Asbestos Testing Laboratories in southern New Jersey. Alarming levels of asbestos fibers were found. Health experts state any amount of asbestos over 100,000 fibers per square centimeter is cause for concern, and some of the schools had millions of asbestos fibers present. Despite having certified asbestos professionals the district can call in to remove and repair asbestos, little has been done to make appropriate repairs. Asbestos is common in schools built before the 1980s since it’s fire resistant and provides good insulation. The fibers are present in a variety of materials, from pipe insulation to floor tiles and ceiling insulation. In 1986 federal lawmakers enacted the Asbestos Hazard Emergency Response Act (AHERA), which requires school districts to inspect their buildings for asbestos-containing materials and prepare plans for action to prevent and reduce asbestos hazards. This includes locating asbestos and ensuring it’s not damaged, encapsulating it to prevent the material from becoming friable (easily crushed or crumbled), or removing the material if it poses a health hazard. The findings in Philadelphia have raised concerns about the health of students and teachers in the district. Asbestos is known to cause a variety of health issues, including mesothelioma, a deadly form of cancer. The needle-like fibers are easily stirred up and can linger in the air for hours to days, making them easily inhaled. A number of tested spaces with high levels of asbestos were areas students frequent, such as hallways, classrooms, and gyms. But asbestos-related diseases can take decades to develop and show symptoms, so the health effects of any potential exposure remain unknown Mesothelioma News Millions of Asbestos Fibers Found in Philadelphia Elementary Schools Posted by Mesothelioma Cancer Alliance editorial staff June 22, 2018 Millions of Asbestos Fibers Found in Philadelphia Elementary Schools PHILADELPHIA, PENNSYLVANIA - Millions of asbestos fibers have been found throughout the Philadelphia school district, according to a joint investigation by The Inquirer and Daily News. The investigation sought to uncover dangerous substances in Philadelphia schools, including asbestos, lead, and mold. Teachers from 11 schools collected samples, which were then analyzed by the International Asbestos Testing Laboratories in southern New Jersey. Alarming levels of asbestos fibers were found. Health experts state any amount of asbestos over 100,000 fibers per square centimeter is cause for concern, and some of the schools had millions of asbestos fibers present. Despite having certified asbestos professionals the district can call in to remove and repair asbestos, little has been done to make appropriate repairs. Have a Question About Asbestos Exposure in Schools? Annette Charlevois is happy to help Asbestos is common in schools built before the 1980s since it’s fire resistant and provides good insulation. The fibers are present in a variety of materials, from pipe insulation to floor tiles and ceiling insulation. In 1986 federal lawmakers enacted the Asbestos Hazard Emergency Response Act (AHERA), which requires school districts to inspect their buildings for asbestos-containing materials and prepare plans for action to prevent and reduce asbestos hazards. This includes locating asbestos and ensuring it’s not damaged, encapsulating it to prevent the material from becoming friable (easily crushed or crumbled), or removing the material if it poses a health hazard. The findings in Philadelphia have raised concerns about the health of students and teachers in the district. Asbestos is known to cause a variety of health issues, including mesothelioma, a deadly form of cancer. The needle-like fibers are easily stirred up and can linger in the air for hours to days, making them easily inhaled. A number of tested spaces with high levels of asbestos were areas students frequent, such as hallways, classrooms, and gyms. But asbestos-related diseases can take decades to develop and show symptoms, so the health effects of any potential exposure remain unknown A top concern is the inability of the school district to repair and remove asbestos when it’s found. Records from the last five years show reports of asbestos problems, many being rated “high priority,” yet remaining in disrepair. Some repairs that were undertaken resulted in slipshod work, and in one case, even increased the amount of asbestos dust in a sample area. The school district has called the newspapers’ reports into question. According to school officials, the method of testing used, known as dust wipe sampling, isn’t as accurate as air testing. Dust wipe samples involve taking a sample of surface dust and determining how many asbestos fibers are present on that surface. Air testing determines how many asbestos fibers are in the air, and therefore at risk of being inhaled. Outside experts argue the importance of dust wipe samples and insist that the results shouldn’t be dismissed. Experts say any result of 100,000 fibers per square centimeter or higher in surface dust should be addressed immediately. Some school locations revealed millions of asbestos fibers per square centimeter. Outrage over the high levels of asbestos fibers caused the Philadelphia school district to act at Olney Elementary School, one of the 11 schools tested. Damaged asbestos areas have been sealed off and students have been relocated from classrooms with high asbestos levels. While this is a step in the right direction, there are still dozens of schools to be repaired in Philadelphia alone, with asbestos still lurking in hundreds of other older school buildings around the country.

survival rates have slowly been improving, thanks to advancements in diagnostic methods and new treatments. Peritoneal mesothelioma patients in particular have seen much improved survival rates, largely due to the success of a newer treatment called hyperthermic intraperitoneal chemotherapy or HIPEC. For patients diagnosed at an earlier stage with minimal metastasis, mesothelioma doctors will typically recommend a combination or multimodal treatment of cytoreductive surgery with HIPEC. The treatments together have seen extended survival and high success rates in many clinical trials and studies so far. What Is HIPEC? As suggested by its name, HIPEC is a special type of chemotherapy applied specifically to abdominal or peritoneal cancers, like colorectal cancer and peritoneal mesothelioma. HIPEC is often described as a heated chemotherapy wash. The treatment consists of chemotherapy drugs (usually a combination of two types) heated between 104 – 107 degrees. The wash is then circulated throughout the abdominal cavity. The HIPEC procedure is generally not used as an individual treatment, but rather as a second step of a combination treatment with cytoreductive surgery. The surgery attempts to debulk and remove as many visible tumors and cancer cells as possible. HIPEC is then applied to kill any remaining cancerous cells that couldn’t be reached in surgery. Many studies have shown HIPEC to be more effective than systemic chemotherapy, since it is more targeted and the drugs are often stronger. Since the treatment is applied after surgery, it unfortunately isn’t an option for all patients. As mesothelioma or other abdominal cancers become more advanced and reach later stages, the cancer cells have likely metastasized or spread too far to be viable for removal. As such, patients diagnosed at stage 3 or stage 4 mesothelioma likely wouldn’t be candidates for this type of treatment. Also, since the treatment is more specialized, it is only available at a handful of cancer centers around the world, which may require patients to travel for treatment. If doctors are able to diagnose the disease earlier, however, patients have sometimes seen substantial improvements in their prognosis because the cancer treatment is so effective. HIPEC Survival Rates for Peritoneal Mesothelioma There have been numerous studies in the last several years around the efficacy of HIPEC for peritoneal mesothelioma, colon cancer, and other gastric cancers. Overall, researchers have found the treatment to be rather successful among these and other cancers, often with minimal side effects compared to traditional chemotherapy and improved survival rates. Various clinical trials focused on peritoneal mesothelioma found great success, with one recent study even seeing 100% overall survival in patients with early-stage disease and successful cytoreduction. For patients with slightly more advanced mesothelioma, the researchers saw patients achieve a median survival of about 98 months, with nearly 59 months disease-free. Considering the average prognosis for peritoneal mesothelioma is just six months to one year, these results prove how effective this multimodal treatment can be in select patients. Other studies have also shown similar success. One report analyzing various clinical trials for a number of malignancies in the peritoneal surface noted a wide range of success. The researchers saw overall survival of 53 months or more for peritoneal mesothelioma patients across a number of studies. They also noted an average 5-year survival rate of 47% – 60%, though other studies have reported even higher survival rates. This is a great improvement against standard chemotherapy, like cisplatin and pemetrexed. Randomized trials have shown peritoneal mesothelioma patients treated with systemic therapy often only see survival of 12 to about 27 months on average. Further, overall mesothelioma survival rates are significantly poorer, with approximately 9% of patients surviving 5 years or longer. In general, these and numerous other studies prove that HIPEC in combination with surgery is an effective treatment option. Have questions about HIPEC? Connect with a doctor to learn more. More Advancements in Chemotherapy Along with the success of HIPEC, researchers have been working on developing other chemotherapy treatments in the hopes of minimizing some of the severe side effects of traditional adjuvant chemotherapy and further improving prognosis. One of the most promising recent advancements comes from doctors overseas with a treatment called Pressurized IntraPeritoneal Aerosol Chemotherapy or Thoracal Aerosol Chemotherapy (PIPAC/PITAC). PIPAC is also available for peritoneal mesothelioma, with a similar methodology as HIPEC. PIPAC is also a targeted chemotherapy application, but unlike HIPEC, doctors deliver the chemotherapy to the abdomen using a pressurized aerosol form. Researchers believe the pressure of the aerosol will enable the chemotherapy treatment to spread throughout the abdomen, much like HIPEC does with the liquid chemotherapy wash. So far, the treatment is only available in early-phase clinical trials, but researchers noted significant tumor regression in these select patients. Since it’s such an early study, PIPAC and PITAC are also currently only available at a handful of treatment centers, but could have a huge impact on cancer care in the future as testing continues. Treatments like HIPEC, PIPAC, and immunotherapy have enabled more mesothelioma patients to achieve longer survival than ever before. Hopefully with continued research, more patients can achieve remission and doctors will become closer to finding a cure.

The Mesothelioma Cancer Alliance is pleased to announce the winner of the Fall 2018 Scholarship, Darwin Arias. Darwin is set to begin his undergraduate career at Columbia University in the fall, with an interest in studying biology, neuroscience, or biochemistry. Throughout his academic career, Darwin has challenged himself to fill his schedule with difficult advanced placement courses and numerous extracurriculars to prepare for college and forge a path to achieve a medical career. Darwin’s mother Judith immigrated to the United States from Puebla, Mexico, when she was 19 in the hopes of a better life. She balanced many part-time jobs in an effort to help support her family in her home country before meeting his father, and eventually starting their own family. The family still faced difficulties, as his parents worked long hours while trying to balance a healthy home life. When his brother was born with serious birth defects, his mother still somehow managed to balance providing her brother special care on top of work and taking care of the household. Though life wasn’t perfect and the family had their ups and downs, Darwin was still able to apply himself in his advanced classes and throw himself into extracurriculars. But seemingly out of nowhere, the life the family knew seemed to come crashing down. A Sudden Cancer Diagnosis “On a mild afternoon in September, my mother’s life was obstructed by an unforeseen malignant tumor found in her right breast by her doctor,” Darwin recalled. “We were stunned. Our family had no history of cancer, and she was just 36.” The family’s routine was turned upside down as years of oncologists visits filled their days. As his mother’s breast cancer spread, the family traveled between the hospital and specialists’ appointments often. For two years, his mother was able to be treated with chemotherapy pills, but unfortunately her condition continued to worsen. As Darwin watched her lose her strength and enthusiasm for life, he stepped up to help her continue fighting and enjoy whatever time she had left. Darwin painted her nails, helped her buy her first wig so she could feel more confident, traveled with her to Mexico to visit her family, and began to help care for his mother more while his dad worked 12-hour days or longer. But through it all, his mom faced worsening side effects of treatment. “I lived months of hardship watching my mother in continuous pain and discomfort, trying my best to not let this stress impede on my adolescent life. Nothing could stop her cancer. It had spread to her brain, left breast, ovaries, and thyroid.” For months near the end, Darwin recalls his mother not being sure if she could endure the pain and suffering of metastatic cancer for much longer. Sadly, his mother passed away surrounded by loved ones in the fall of 2017. Find support and resources when facing cancer Life After Cancer After his mother’s death, Darwin and his family returned to her village in Mexico to fulfill her wish of being buried there. As Darwin reflected on her past life in the village and all their family had endured over the years, he realized how much he appreciated the life his mother worked so hard to give him. Even in the face of this tragedy, Darwin knew he couldn’t let his sorrow hold him back from his future. “Overcoming the loss of a parent to terminal illness beginning my senior year of high school has indeed shaped my outlook on life,” Darwin explained. “I have become much more loving towards my closest peers, who provided me with love and support during my extraordinarily difficult time. I have developed a true appreciation for my six-year-old brother, who I now feel gifted with to guide.” He also continued to pour himself into his school work, even becoming part of a highly selective clinically based program through Northern Westchester BOCES, New Visions Health. Through the program, Darwin was able to take honors courses while also experiencing clinical rotations in a number of departments, including radiology and pharmacology. “My mother’s death has motivated me to pursue a higher education in legacy of her hard work and perseverance,” Darwin continued. “My experiences have shaped me to seek to bring optimism and joy to the lives of others, specifically by pursuing a career as a medical doctor. Observing the care that so many community members and medical staff gave to my mother, has now galvanized me to study medicine, with the goal of one day being able to heal and comfort families, specifically immigrant families who may not know what to do in a time of medical crisis.” Darwin hopes his collegiate career at Columbia University will help drive forward his future medical career in his mother’s honor. “I envision myself pursuing a medical career, being an active community member, and bringing positive change to the lives of others, perhaps even as an oncologist.” The Mesothelioma Cancer Alliance is honored to present the scholarship to Darwin and see the difference he can make in the oncology field as he furthers his education and pursues his career.